Intelligent Humor - http://www.xe.net/inthumor/ Offbeat comic, also known as "Big Meaty Chunks", by Chris Williams. Collected by Steven Dengler of Xenon Labs.
The Infirm - http://www.baywalk.com/cartoons/infirm.htm Humor comic about a first-year associate attorney.
In the Dark - http://www.radialpistonengine.netfirms.com/ Demons and Angels. Where the battle to free Demonkind from the Netherworld is about to break out. By Alex.
Ida Arts - http://www.angelfire.com/id2/iddproductions/ A gallery of cartoons about a misfortunate cat named Cas.
Inktank.com - http://www.inktank.com Two strips: Angst Technology, about a game development company, and Weak-end Warriors, about paintball.
In the Bleachers - http://www.gocomics.com/inthebleachers/ Steve Moore's syndicated humor cartoon about sports.
Isometric - http://isometric.spaceninja.com A comic strip drawn entirely with isometric perspective cubes.
Insane Add-a-Panel - http://www.zerotv.com/addapanel/panel.cfm?pt=multi Add a panel to this comic. An always changing comic.
Intershadows - http://www.intershadows.com/ Features an archive of the title, a gallery of sketches and illustrations, and the series Coolville. By Kathleen Jacques.
The Imp - http://www.barstowproductions.com A humor strip about hell, by Jose Arroyo and Robin Reed.
The Invisible Life of Poet - http://www.lifeofpoet.com/ Social commentary through the eyes of a child. By Christopher Wilson.
Inepto.com - http://www.inepto.com/ Lampoons ineptitude at all levels of society, from customer service to CEOs and politicians.
Is This Tomorrow? - http://www.isthistomorrow.com/ Features collections, a history, and archives of various strips. Created by Kelly Shane and Woody Compton.
Interns - http://www.internsthecomic.com/ Features three interns as they work at a prominent comic book publisher. Includes character bios.
Isk - http://users.tpg.com.au/rocket48/isk A web comic about a small tormented child.
Innies and Outties - http://www.inniesandoutties.com Funny comic strip about two latchkey kids imagining their way through the enchanted land of suburbia. By Leonard Cachola.
I'm Blue - http://www.blue-comic.com/ Highlights the trials, tribulations and comedy of the main character Blue Veers, and her friends Celia, Derec, Tyger, Max, and Duo.
Ink On Paper - http://www.geocities.com/bobquackers/comix/ We've got Magic Pig, Supa Fly, Bob Quackers and more strips.
Insane Comics - http://www.geocities.com/insane_comics/ A normal sprite comic site but with a twist. Include Super Heroes In Training, Unit 003, 8 Bit Insanity, and Megaman SC.
Irrelevant - http://geocities.com/irrelevant_comic/ Contains quizzes, polls and such, as well as the weekly toon.
In Real Life - http://saywhatpb.comicgenesis.com/ Following the adventures of Mario, Mega Man, and Link when they are sucked out of the Super NES.
In The Puddle - http://www.inthepuddle.com Semi-reality webcomic by Cique Johnson, about bisexual, lesbian and straight young adults in Philadelphia - starring artist and pastafarian Cique, her guy, and pet bat.
Irregular Webcomic! - http://www.irregularwebcomic.net/ Lego and gaming photo comics by David Morgan-Mar.
Ignaki - http://www.ignaki.com/eng.htm A collection of cartoons about food, computers, art; translated into English. By Ignacio Lafferriere.
Idiom Syndrome - http://idiomsyndrome.comicgenesis.com/ A photo-webcomic with random humour for the most part.
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